What is Beta Glucan? - Yeast Education

Beata Glucan Diffrences
Yeast Wall


Yeast has a strong cell wall, and occupying about 30% of total cell mass, approximately 90% cell

 wall containing mannoprotein consisting outer membrane and glucan consisting inner membran

e, and contained small amount of chitin(1-3%) and lipid(2-5%). Mannoprotein and glucan are

similar in cell wall (Fleet, G. H. 1991).


It is derived from several sources, including yeast, bacteria, fungi and cereals, such as oats, barley and rye. Each type of beta glucan has a unique structure in which glucose is linked together in different ways, giving them physical properties.

Beta glucan is a complex carbohydrate or biopolymer of glucose, a simple sugar.

beta 1,3 glucan derived from bacteria and algae is linear, making it
useful as a food thickener.
Yeast beta glucan is branched with ß1,6 and ß1,3 glucans,
enhancing its ability to bind and stimulate macrophages.
The chemical structure of beta 1,3- glucan is dependent on the
source and, based on extensive published research, it is widely
accepted that the beta 1,3-glucan purified from baker's yeast
(Saccharomyces cerevisiae) is the most potent anti-infective beta-
glucan immunomodulator .
Yeast-derived beta 1,3-glucans work, in part, by stimulating the
innate anti-fungal immune mechanisms to fight a range of foreign


Immune System Components:

Innate Immune Response

vAcquired Immune Response 


The immune system has two components, the innate and the acquired. Beta glucan works to activate both.

 As we all know, the immune system protect us from foreign invaders and helps keep us healthy. What is less known is that beta glucan is scientifically proven to strengthen the immune system.

In the innate immune system, beta glucan binds with the defences against them.

macrophages, a type of white blood cell whose job is to detect intruders and coordinate the body's





The stimulated macrophages then communicate the intruder's presence to the body's other defenders. Together the macrophages

and the cells of the acquired immune system join the fight.



Using the information transmitted from the macrophages, B-cells begin producing antibodies and T-cells, which are specialized cells trained to kill the invaders.


The antibodies, working with the innate immune system, bind foreigners into clusters which helps to destroy them.

 The intruders are then engulfed by macrophages. This is how the immune system rids the body of harmful invaders.



The health and strength of your immune system directly effects your body's ability to protect itself. Beta glucan can support your immune system, and help it achieve peak performance.

Development of Yeast IS2 (Patented)

  General Baker’s yeast - 8 000 000 type -> Mutation - 760 type ->Isolation ->    

 Culture Experiment - 4 type -> Stabilization - 1 type

   Isolation of yeast glucan and animal experiment for efficacy



 When activated by beta glucan, macrophages go on high alert and their ability to identify and destroy foreigners is heightened. Through a process called "phagocytosis", macrophages devour invaders like pac-man. Research shows that macrophages fortified by beta glucan are

better able to rally the body's defenses.

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